Protein
Also known as: dietary protein, protein supplements, whey protein, casein protein, pea protein, rice protein, Protein
Overview
Protein is a macronutrient critical for the growth, repair, and maintenance of tissues in the human body. Made up of long chains of amino acids, proteins are involved in almost every cell function. Natural sources of protein include meat, fish, cheese, eggs, legumes, and grains. As nutritional supplements, proteins are often utilized to support muscle growth, performance, and recovery, especially in athletes. The efficacy of protein supplementation is well-documented through extensive research, including systematic reviews and meta-analyses, highlighting proteins' ability to enhance muscle protein synthesis, strength, and overall physical performance.
Benefits
Protein supplementation offers numerous evidence-backed benefits: 1) It significantly enhances muscle strength and size, especially when combined with resistance exercise, improving one-repetition maximum and fat-free mass (high-quality evidence). 2) It aids endurance performance more efficaciously when coupled with carbohydrates. 3) In elderly populations, high protein intake mitigates complications and promotes better physical functioning, reducing hospital readmissions. The benefits are most pronounced in individuals engaged in resistance training and in older adults, with observable effects typically appearing within weeks to months of consistent supplementation.
How it works
Protein supplementation functions primarily by supplying essential amino acids necessary for muscle protein synthesis (MPS). Specifically, leucine, an essential amino acid, plays a pivotal role in regulating MPS. The supplementation boosts the body's potential to repair and build muscle tissue, interacts with the muscle and skeletal systems, and positively influences muscle mass over time. The absorption rates may differ by protein type, with whey protein being particularly highly bioavailable, enhancing its efficacy.
Side effects
Protein supplementation is generally safe when consumed at recommended levels. Common side effects include gastrointestinal discomfort and bloating, occurring in more than 5% of users. Less commonly (1-5%), allergic reactions can occur, especially with specific protein sources like dairy or soy. Rarely (<1%), severe allergic reactions may occur. Additionally, those with compromised kidney function should consult healthcare providers before use due to potential interactions. Caution is advised for populations such as pregnant women and children, who should seek medical guidance to assess safety and appropriateness of protein supplementation.
Dosage
The minimum effective protein intake for general health is around 1.2 g/kg/day, while athletes may require 1.6 to 2.2 g/kg/day to support muscle growth and strength effectively. It is considered safe to consume protein up to 3.0 g/kg/day, although individual tolerances may vary. Post-workout protein ingestion is particularly beneficial for muscle recovery. The choice of protein form, such as whey or casein, can influence absorption rates, and timing of intake may also enhance efficacy. No specific cofactors are required for protein absorption, but adequate hydration is recommended.
FAQs
How much protein should I take?
The optimal amount varies by activity level; generally, 1.2 to 2.2 g/kg/day is recommended based on goals.
Is protein supplementation safe?
Generally safe for healthy individuals; consult with a healthcare provider if you have kidney issues.
When should I take protein?
Post-workout protein supplementation is beneficial for muscle recovery.
What results can I expect from protein supplementation?
With consistent training and supplementation, expect improved muscle strength and endurance.
Does more protein lead to more muscle gains?
Excessive protein intake doesn’t correlate linearly with muscle gains beyond certain thresholds.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/28698222/ – This systematic review analyzed 49 studies with 1863 participants, showing that protein supplementation significantly increases muscle strength and size during prolonged resistance exercise training, although effects diminish with age.
- https://pubmed.ncbi.nlm.nih.gov/22212388/ – This review included 36 randomized controlled trials with 3790 participants, primarily elderly, indicating that high protein supplementation reduces complications and improves grip strength, suggesting clear clinical benefits in older populations.
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1455728/full – This Bayesian meta-analysis of 28 studies involving 373 athletes found that protein intake notably improves endurance performance, especially when combined with carbohydrates; however, the overall performance enhancement was modest.
Supplements Containing Protein

Bee Pollen Granules
Vitamin World

Vitamins For The Hair
Vitamin World

Cell Rush
All American EFX

LBA PRO Chocolate Syrup
All American EFX

LG5 PRO
All American EFX

LBA PRO Vanilla Glaze
All American EFX

N'Gage Glacier Punch
Axis Labs

Green SuperFood All Natural Drink Powder
Amazing Grass

Maximum Nutrition Vanilla Bean
GNC Mega Men

Maximum Nutrition Vanilla Creme
GNC Women's Ultra Mega

Spirulina Powder
Vitamin World
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