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Shi Chang Pu Root Extract

Also known as: Acorus tatarinowii, Acorus calamus var. angustatus, Acorus calamus var. tatarinowii, Sweet Flag, Calamus, Shi Chang Pu, Acorus calamus

Overview

Shi Chang Pu root extract, derived from the rhizome of *Acorus calamus*, is a traditional herbal remedy primarily used in Chinese medicine for its potential cognitive and neurological benefits. Traditionally, it has been employed to address gastrointestinal issues, enhance cognitive function, and serve as a sedative. Key bioactive compounds, particularly asarone, are believed to impart neuroprotective effects. Despite its widespread use, systematic reviews and high-quality clinical studies verifying the efficacy and safety of Shi Chang Pu are limited, necessitating further research to substantiate the claims associated with its traditional applications. The extract is commonly consumed in various forms, often as a decoction or in combination with other herbs, reflecting its longstanding position in traditional herbal practices.

Benefits

The primary benefits of Shi Chang Pu include potential improvements in cognitive function and neuroprotection, primarily evidenced through preclinical studies. While these findings suggest possible benefits, clinical data are scarce, and evidence is not robust. Additionally, traditional uses suggest sedative effects and gastrointestinal benefits; however, specific populations that may benefit the most from its use are not well-documented. As a result, no quantified effect sizes exist due to the absence of high-quality clinical trials. Such limitations underscore the need for more rigorous research to validate the traditional claims surrounding Shi Chang Pu.

How it works

Shi Chang Pu is thought to exert its neuroprotective effects through the modulation of inflammatory pathways and potentially antioxidant mechanisms. It primarily interacts with the central nervous system and the gastrointestinal system, though specific molecular targets remain poorly defined. The limited data on its absorption and bioavailability further complicate understanding its overall mechanism of action, indicating a need for additional studies to elucidate these interactions.

Side effects

Shi Chang Pu is generally considered safe for traditional use, but comprehensive modern safety data are lacking. Common side effects are not well-documented, although potential allergic reactions or mild gastrointestinal upset may occur. Rare side effects are currently unknown due to the lack of extensive safety studies. Caution is advised regarding possible interactions with sedatives and anticholinergic drugs. Additionally, it is contraindicated in pregnant and breastfeeding individuals due to insufficient safety data. Special care should be taken when used by children or individuals with severe medical conditions, underscoring the importance of further research on its safety profile.

Dosage

The dosing guidelines for Shi Chang Pu are not well established, with traditional usage varying significantly. As no standardized dosage exists, minimum effective or maximum safe doses have not been defined. Timing considerations for use are also unspecified, and the extract is typically consumed as a decoction or combined with other herbs. The factors affecting absorption remain unclear, and there are no identified cofactors, reinforcing the necessity for more research to determine appropriate dosing practices.

FAQs

Is Shi Chang Pu effective for cognitive improvement?

While traditionally believed to enhance cognitive function, there is limited clinical evidence to support this claim, necessitating caution.

Are there any known side effects?

Common side effects aren't well-documented, but potential allergic reactions and gastrointestinal upset have been noted.

What is the recommended dosage?

No standardized dosage exists for Shi Chang Pu; traditional use varies widely and lacks formal guidelines.

Can I use Shi Chang Pu during pregnancy?

It is contraindicated during pregnancy and breastfeeding due to insufficient safety data.

Is there any risk of drug interactions?

Potential interactions with sedatives or anticholinergic drugs are possible, so consulting a healthcare provider is advisable.

Research Sources

  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1341074/full – This study explores the neuroprotective effects of herbal combinations used in traditional Chinese medicine, indirectly highlighting mechanisms relevant to Shi Chang Pu, while noting the need for more focused research.
  • https://pubmed.ncbi.nlm.nih.gov/26433766/ – This article reviews cognitive benefits associated with various herbal drugs, providing context for Shi Chang Pu among related herbs in the field of cognitive health.
  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1268000/full – Exploring herbal medicine efficacy, this review spotlights the broad category of herbal remedies, underscoring the limitations of direct evidence related to Shi Chang Pu.
  • https://journals.lww.com/md-journal/fulltext/2021/09240/chinese_herbal_medicine_for_mild_cognitive.6.aspx – This systematic review discusses the role of Chinese herbal medicine in treating mild cognitive impairment, providing insights that could be informative for understanding Shi Chang Pu's place in herbal therapy.

Supplements Containing Shi Chang Pu Root Extract

No Worries by Good Pharma
63

No Worries

Good Pharma

Score: 63/100

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