Tree Peony Root Bark Extract
Also known as: Tree Peony, Moutan, Paeonia suffruticosa
Overview
Tree Peony root bark extract is derived from the *Paeonia suffruticosa*, a plant recognized in traditional Chinese medicine for its anti-inflammatory, antioxidant, and overall health-promoting properties. It consists of various bioactive compounds including phenols, flavonoids, and terpenoids. While it is traditionally used for medicinal purposes and as a cosmetic skin-conditioning agent, scientific research on its efficacy is still emerging. Available studies point to its potential benefits, mainly based on its constituent compounds, but high-quality clinical trials are limited, suggesting an ongoing need for further investigation into its health effects and biochemical mechanisms.
Benefits
Evidence suggests that *Paeonia suffruticosa* contains compounds with anti-inflammatory and antioxidant properties. However, direct evidence specific to Tree Peony root bark extract is limited. Some studies indicate potential cardiovascular protection and neuroprotective effects linked to the bioactive compounds, but robust clinical evidence is scarce with most findings based on traditional uses. Effect sizes and clinical significance are not well-established due to the lack of large-scale studies, and there are no documented population-specific benefits at this time.
How it works
The anti-inflammatory and antioxidant properties of Tree Peony root bark extract are thought to originate from its bioactive compounds. These compounds may modulate inflammatory pathways and reduce oxidative stress, potentially interacting with various body systems such as the immune and cardiovascular systems. Detailed interactions and specific molecular targets, however, remain under-researched.
Side effects
Tree Peony root bark extract is generally considered safe based on traditional usage, but thorough studies on its safety profile are lacking. Common, uncommon, or rare side effects have not been well-documented in the literature. There is also limited information on potential drug interactions and contraindications. Women who are pregnant or breastfeeding are advised to consult healthcare providers due to insufficient data on safety in these populations.
Dosage
Recommended dosages for Tree Peony root bark extract have not been established due to insufficient research. The minimum effective and optimal dosage ranges are currently undefined, and there is no established maximum safe dose. Guidelines on timing and the form of extraction used to improve absorption are also lacking. As with any herbal supplement, it is advisable to seek professional consultation for personalized dosage recommendations.
FAQs
Is Tree Peony root bark extract safe to use?
While generally considered safe, there is limited formal safety data. It's best to consult a healthcare provider, especially if you are pregnant, breastfeeding, or taking medications.
What are the main benefits of Tree Peony root bark extract?
It may offer anti-inflammatory and antioxidant benefits, but evidence is not strong and further research is needed to confirm these effects.
How should I take Tree Peony root bark extract?
Dosage recommendations are not well-established. Consult a healthcare provider for guidance tailored to your specific health needs.
Does Tree Peony root bark extract interact with medications?
Potential drug interactions have not been extensively studied, so consult with a healthcare professional if you're on other medications.
What should I be aware of regarding side effects?
Side effects are not well documented. Consult a healthcare provider for advice, particularly if you have existing health conditions.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/28748514/ – A meta-analysis demonstrating that total glucosides of peony combined with methotrexate are more effective than methotrexate alone for rheumatoid arthritis treatment. However, the quality of included trials was poor.
- https://pubmed.ncbi.nlm.nih.gov/31048131/ – This metabolomics analysis identified various bioactive compounds, including flavonoids and terpenoids, in multiple species and varieties of tree peonies, focusing on metabolite identification rather than clinical effects.
- https://www.cir-safety.org/sites/default/files/SLR_PaeoniaSuffruticosa_032024.pdf – Safety assessment indicating low oral toxicity of Paeonia suffruticosa-derived ingredients; limited to animal studies without sufficient human clinical data.
- https://dsld.od.nih.gov/ingredient/Tree+Peony+root+bark+extract – Summary of properties and traditional uses of Tree Peony root bark extract, with an emphasis on the need for further research on its health benefits.
- https://pubs.rsc.org/en/content/articlelanding/2023/fo/d3fo04094a/unauth – An exploration of the composition and potential health effects of various *Paeonia* extracts, highlighting the biological activity of its phenolic compounds.
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