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Whole Coffee Fruit

Also known as: Coffee Cherry Extract, Coffea arabica, Coffea canephora, Whole Coffee Fruit

Overview

Whole Coffee Fruit (WCF) is derived from the fruit of the coffee plant, specifically *Coffea arabica* and *Coffea canephora*. Traditionally considered a waste product, this fruit is now recognized for its high polyphenol content and potential health benefits. WCF is commonly consumed as a dietary supplement in powdered or extract form, prized for its antioxidant and neuroprotective properties. Ongoing research highlights its ability to influence brain health through mechanisms such as elevating Brain-Derived Neurotrophic Factor (BDNF). While initial findings are promising, further investigation into its broader health effects and bioavailability is necessary.

Benefits

Whole Coffee Fruit is associated with several key benefits, particularly its ability to significantly increase plasma levels of Brain-Derived Neurotrophic Factor (BDNF), which plays a crucial role in brain health and neuroplasticity. A study found that a single dose of Whole Coffee Fruit Concentrate (WCFC) can elevate BDNF levels by approximately 91% to 143% compared to baseline, suggesting significant neuroprotective potential. Moreover, early evidence indicates possible enhancements in cognitive performance, although this area requires more detailed research. Currently, the benefits appear most relevant for healthy individuals, highlighting WCF's importance in supporting overall brain health, particularly in enhancing neurotrophic factors within a short timeframe post-ingestion.

How it works

The mechanism by which Whole Coffee Fruit exerts its effects is not fully elucidated but is believed to be linked to its high polyphenol content, particularly procyanidins, which may stimulate the release of BDNF. This neurotrophic factor is essential for the growth, maintenance, and survival of neurons, implicating WCF in neural health. WCF's interaction with the nervous system likely enhances neurotrophic support, fostering an environment conducive to brain function and resilience.

Side effects

Whole Coffee Fruit is generally considered safe in short-term studies, with no significant adverse effects noted. Common issues might include palatability problems, primarily reported in animal studies. Rare or uncommon side effects have not been documented extensively. Additionally, safety assessments have indicated no genotoxic or mutagenic effects resulting from WCF consumption. There are currently no known drug interactions or contraindications associated with its use. However, the safety of WCF in specific populations, including pregnant women, children, and those with chronic conditions, has not been conclusively established due to insufficient data. As with any supplement, it is advisable to consult with a healthcare professional before use.

Dosage

The minimum effective dose of Whole Coffee Fruit Concentrate (WCFC) to observe significant increases in BDNF levels is approximately 100 mg, typically taken in powdered form. Higher dosages are not well-studied, and while animal studies suggest a high tolerance, human data on maximum safe doses remain limited. The effects of WCF can be felt within 60 minutes of ingestion, making timing an important factor for those interested in its cognitive benefits. Due to the lack of extensive research on optimal dosage ranges and absorption factors, individual responses may vary, and careful consideration is recommended when considering higher doses.

FAQs

Is Whole Coffee Fruit safe for long-term use?

While WCF is considered safe for short-term use, there is insufficient data to establish its long-term safety.

How quickly can I expect to see results after taking WCF?

Most effects, particularly the increase in BDNF levels, are typically observed within 60 minutes of ingestion.

Can WCF support cognitive health?

Yes, by increasing BDNF levels, WCF may support cognitive functions, although more research is needed.

How does WCF differ from coffee bean extracts?

WCF contains unique phytonutrients and polyphenols not found in coffee bean extracts, potentially offering distinct health benefits.

Research Sources

https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/modulatory-effect-of-coffee-fruit-extract-on-plasma-levels-of-brainderived-neurotrophic-factor-in-healthy-subjects/8B291E8D053143AA5A8D33B65496B034 – This study demonstrated that a single dose of coffee fruit extract significantly increases plasma BDNF levels in healthy subjects, indicating potential neuroprotective effects. However, it involved a small sample size and short follow-up duration.
https://pubmed.ncbi.nlm.nih.gov/20600539/ – Pilot study findings supported that whole coffee fruit concentrate notably increased BDNF levels within an hour of ingestion, with effects lasting for at least two hours. Limitations included a small cohort and the need for longer-term studies.
https://www.scirp.org/journal/paperinformation?paperid=36447 – This research focused on the safety of CoffeeBerry products derived from whole coffee fruit, reporting no genotoxic or mutagenic effects, and demonstrating good tolerance in animal studies, though caution is advised when extrapolating to human populations.
https://pubmed.ncbi.nlm.nih.gov/23312069/ – Safety assessments in these studies confirmed Whole Coffee Fruit's lack of adverse effects and suggested a generally high tolerance in early clinical evaluations, though human data remains limited.
https://www.mdpi.com/2072-6643/16/14/2348 – Comprehensive reviews highlighted the nutritional profile and the potential health advantages of coffee cherries, emphasizing their antioxidant properties while acknowledging the necessity for more solid clinical evidence.