Yerba Mate Leaf Extract
Also known as: Yerba Mate, Mate, Paraguay Tea, Ilex paraguariensis
Overview
Yerba Mate, scientifically known as *Ilex paraguariensis*, is an herbal tea derived from the dried leaves of the *Ilex paraguariensis* plant, native to South America. It is traditionally consumed as a beverage and dietary supplement, prized for its stimulant properties due to its caffeine content. Yerba Mate is rich in bioactive compounds, including polyphenols, xanthines (caffeine, theobromine), caffeoyl derivatives, and saponins, contributing to its potential health benefits. Research suggests that Yerba Mate may aid in weight loss, improve cardiovascular health, and provide antioxidant effects. It is available in various forms, primarily as dried leaves for tea preparation, and is increasingly found in supplement formulations. While research is ongoing, existing studies indicate promising effects on metabolism, antioxidant activity, and overall well-being. However, the quality of evidence varies, and further studies are needed to confirm these benefits.
Benefits
Yerba Mate offers several evidence-based benefits, primarily related to weight management and metabolic health. A meta-analysis of clinical trials demonstrated significant reductions in body weight, BMI, and waist circumference with *I. paraguariensis* consumption, particularly in dyslipidemic, obese, and diabetic patients. Studies also indicate consistent improvements in metabolism, including enhanced antioxidant and anti-inflammatory activities. Furthermore, Yerba Mate has been associated with cardiovascular benefits, such as protective effects on liver cells and reduced inflammation. Secondary benefits include potential improvements in exercise performance, mood, and neuroprotection, although the evidence for these is less robust. The effect sizes for weight loss and BMI reduction are clinically significant, with some studies reporting a mean difference in BMI reduction of -1.13 kg/m². Benefits have been observed in interventions lasting from several weeks to a few months.
How it works
Yerba Mate's mechanism of action is attributed to its bioactive compounds, especially polyphenols and caffeine. These compounds interact with metabolic, antioxidant, and anti-inflammatory pathways. Caffeine stimulates the central nervous system, promoting alertness and focus. Yerba Mate affects the cardiovascular system by reducing inflammation and improving metabolic parameters. Its antioxidant effects, primarily from polyphenols like caffeic acid and chlorogenic acid, neutralize free radicals, potentially contributing to anti-aging and anticancer properties. The bioavailability of these compounds is influenced by factors such as genotype characteristics and metabolization processes, which can vary by region.
Side effects
Yerba Mate is generally considered safe for most adults when consumed in moderation. Common side effects, primarily due to its caffeine content, include jitteriness, insomnia, and increased heart rate. Uncommon side effects, though data is limited, may include an increased risk of certain cancers (mouth, throat, lungs) with high consumption, especially when combined with smoking or alcohol. Rare side effects are not well-documented. Yerba Mate can interact with various medications, supplements, and health conditions due to its caffeine and polyphenol content; consulting a healthcare provider is advisable before consumption. Pregnant individuals should also seek medical advice due to the caffeine content. High consumption should be avoided by individuals at risk for certain cancers and those sensitive to caffeine. A daily cup made with 3 grams of leaves has been studied and found safe for up to 12 weeks.
Dosage
The minimum effective dose of Yerba Mate is not definitively established, but a daily cup made with 3 grams of leaves has been studied and found safe for up to 12 weeks. Typical consumption involves 1-2 cups per day, each prepared with 3 grams of dried leaves. Optimal dosages for specific health benefits require further research. Consuming more than 1-2 liters (4-8 cups) per day may increase the risk of certain cancers and other adverse effects. While there are no specific timing recommendations, it is traditionally consumed throughout the day. Bioavailability can be influenced by factors such as genotype and metabolization processes. No specific cofactors are required for its absorption or efficacy.
FAQs
Is Yerba Mate safe to consume?
Moderate consumption is generally safe, but high consumption over long periods may have health risks, especially in combination with other lifestyle factors like smoking and alcohol.
When is the best time to drink Yerba Mate?
It can be consumed at any time of day, but the caffeine content should be considered to avoid sleep disturbance. Avoid drinking it close to bedtime.
What results can I expect from drinking Yerba Mate?
Weight loss, improved metabolic parameters, and antioxidant effects can be expected, but individual results may vary. It works best when combined with a healthy diet and lifestyle.
Can Yerba Mate replace a healthy diet?
No, it is not a replacement for a healthy diet and lifestyle; it should be used as part of a balanced regimen to support overall health and well-being.
Research Sources
- https://www.scielo.br/j/bjps/a/BrcpCjnRS7mpSsX3WGhjYSr/ – This systematic review and meta-analysis of 22 clinical trials found that *I. paraguariensis* consumption significantly reduced body weight, BMI, and waist circumference, particularly in patients with dyslipidemia, obesity, and diabetes. The study highlights the potential of Yerba Mate as a weight management aid, but notes the moderate to very low certainty of evidence due to the high risk of bias in some included studies.
- https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/yerba-mate/faq-20058343 – This resource from Mayo Clinic provides general information about Yerba Mate, including its safety and potential side effects. It notes that Yerba Mate is generally safe in moderate amounts but can cause caffeine-related side effects like jitteriness and insomnia. It also advises pregnant individuals to consult a healthcare provider before consuming Yerba Mate due to its caffeine content.
- https://pubmed.ncbi.nlm.nih.gov/32588612/ – This review of scientific literature discusses the health effects of Yerba Mate, including its protective effects on liver cells, stimulation of the central nervous system, and anti-inflammatory effects. It provides a broad overview of the potential health benefits of Yerba Mate, highlighting its positive effects on the cardiovascular system. However, it lacks the rigor of a systematic review.
- https://pubmed.ncbi.nlm.nih.gov/36647770/ – This systematic review analyzed 32 studies and found consistent effects of Yerba Mate on metabolism improvement, antioxidant, and anti-inflammatory activities. It also noted benefits for body weight, exercise performance, mood, and cardio- and neuroprotective effects. The review acknowledges the high risk of bias in many studies, resulting in moderate to very low certainty of evidence.
- https://matchaalternatives.com/blogs/the-ma-blog/antioxidant-benefits-mate-moringa-tulsi – This blog post discusses the antioxidant benefits of Yerba Mate, highlighting its rich polyphenol content, including caffeic acid, chlorogenic acid, quercetin, and rutin. These polyphenols act as antioxidants by neutralizing harmful free radicals. The post emphasizes the role of Yerba Mate in promoting overall health through its antioxidant properties.
Supplements Containing Yerba Mate Leaf Extract

Ginkgo Biloba Plus
GNC Herbal Plus Standardized

Refine
GNC Beyond Raw

Battle Fuel
MusclePharm

Amplified Muscle Igniter 4X
GNC Pro Performance AMP

AMP Explosive Energy Metabolizer
GNC Pro Performance AMP
Amplified Muscle Igniter 4X
GNC Pro Performance AMP

Maximum Strength + Energy
Estroven

Estro Support Max + Energy
21st Century

Energy Formula
GNC Herbal Plus

Ginkgo Biloba Plus
GNC Herbal Plus

Maca Complex
GNC Herbal Plus

Lineaslim Metabolism Activator
Apax USA
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