Folivane-Plus with Ascorbic Acid Precursors

Trigen Laboratories

#Other

Safety35

Efficacy60

Transparency75

Based on Examine, Wikipedia, and 23 other sources

Overview

This product focuses heavily on Folic Acid and Iron. While the Folic Acid dose is clinically effective for specific conditions (e.g., neural tube defect prevention, homocysteine reduction), the iron content is profoundly high and likely to cause toxicity in individuals without severe iron deficiency. The other B vitamins are present in very high quantities, far exceeding daily recommendations, which limits their broad applicability as a general multi-vitamin and raises safety concerns due to excessive dosing.

The Good

Provides a robust dose of Folic Acid (1000 mcg), which is highly effective for women of childbearing age to prevent neural tube defects.

Contains a very high dose of Iron (125mg), which can be highly effective for individuals diagnosed with significant iron deficiency anemia under medical supervision.

Includes a comprehensive array of B vitamins (Thiamine, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Biotin, Pantothenic Acid) that support various metabolic functions and energy production.

The Bad

High dose of Iron (125mg per serving) significantly exceeds UL for most adults, posing a high risk of iron overload and toxicity including organ damage, especially for individuals not specifically diagnosed with iron deficiency anemia.

Very high doses of B vitamins (Thiamine, Riboflavin, Niacin, Vitamin B6, Folate) are provided which are far beyond typical daily needs and may lead to negative interactions or mask other deficiencies, such as the high amount of Folic Acid potentially masking a B12 deficiency.

The term "Ascorbic Acid Precursors" is vague and does not specify exact compounds or their quantities, making efficacy and safety assessment difficult beyond the listed Vitamin C (210mg) which is itself not a precursor.

Is it for you?

Best For: Individuals seeking general nutritional support, those with potential folic acid deficiencies, individuals looking to support vitamin C levels

Skip If: You are on medications that interact with folic acid, or have a known allergy to any ingredients.