ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Optimized Tryptophan Plus

Optimized Tryptophan Plus

Life Extension

#Sleep Aid
58
Safety55
Efficacy60
Transparency85
Based on Examine, Wikipedia, and 23 other sources

Overview

Optimized Tryptophan Plus is a blend of L-Tryptophan, Niacin, L-Lysine, and a proprietary blend aimed at supporting sleep, mood, and overall cellular function. While the primary ingredient, L-Tryptophan, is well-researched for improving sleep, the additional components, specifically the proprietary blend, lack thorough studies as combined. The effectiveness of this specific formulation needs more clinical evidence.

The Good

L-Tryptophan may improve sleep quality and mood through serotonin and melatonin production.

Niacin may enhance cellular energy production and blood lipid profile.

L-Lysine may support immune function.

The Bad

Potential for serotonin syndrome if taken with other serotonergic drugs or in susceptible individuals.

May cause drowsiness, gastrointestinal issues, headaches, or blurred vision in some individuals.

Complex interactions between ingredients require medical oversight.

Is it for you?

Best For: Individuals seeking sleep support, mood enhancement, stress reduction

Skip If: You are pregnant, nursing, taking antidepressants, or have a medical condition without consulting a doctor.

Ingredients Analysis

Niacin

66 mg

L-Tryptophan

1000 mg

L-Lysine

250 mg

Proprietary Tryptophan Plus Blend

285 mg

Perluxan Hops Standardized Extract

Rosemary Standardized Extract

How to Use

Take one (1) capsule before bedtime, or as recommended by a healthcare practitioner.

Frequency:

Daily

Best Time:

Evening

When:

Before bedtime, with or without food

Who Should Use This

Best For:

Individuals seeking sleep support, mood enhancement, stress reduction

Similar Products

L-Tryptophan by BulkSupplements.com

L-Tryptophan

BulkSupplements.com

l-Tryptophan by Isotonix

l-Tryptophan

Isotonix

L-Tryptophan by Lidtke

L-Tryptophan

Lidtke

L-Tryptophan by Douglas Laboratories

L-Tryptophan

Douglas Laboratories

L-Tryptophan by California Academy of Health

L-Tryptophan

California Academy of Health

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement by Vetriscience®

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement

Vetriscience®

Recommended Articles

5 Foods Disrupting Your Sleep Quality

5 Foods Disrupting Your Sleep Quality

Caffeine, sugar, spicy foods, fatty meals, and alcohol consumed before bed can significantly disrupt sleep quality.

Top Natural Sleep Aids: Ingredients for Better Rest

Top Natural Sleep Aids: Ingredients for Better Rest

Melatonin, magnesium, lavender, and valerian root are key ingredients that can significantly improve sleep for those with difficulties.

Best Sleep Aids for Night-Shift Nurses

Best Sleep Aids for Night-Shift Nurses

Melatonin, along with proper sleep hygiene, significantly improves sleep quality for night-shift nurses.

Vitamin B6 Overdose: Signs & Solutions

Vitamin B6 Overdose: Signs & Solutions

Vitamin B6 overdose can lead to sensory neuropathy; managing intake is crucial for health.