Cassia Twig Extract
Also known as: Cassia twig, Chinese cinnamon, Cassia cinnamon, Cinnamomum cassia
Overview
Cassia twig extract, derived from the bark of the *Cinnamomum cassia* tree native to China and Southeast Asia, is a common ingredient in traditional Chinese medicine. Known for its robust flavor, it's traditionally used for inflammation, digestive issues, and diabetes management. The extract is believed to possess anti-inflammatory and antioxidant properties. While some clinical research supports its potential benefits, particularly in improving insulin sensitivity and blood sugar control, the evidence is not as robust as for other supplements, and studies often yield conflicting results. Cassia cinnamon contains bioactive compounds like cinnamaldehyde, which are thought to contribute to its effects. It is generally considered safe in moderate amounts but should be used cautiously due to potential side effects, including liver damage from high coumarin content.
Benefits
Cassia cinnamon may improve insulin sensitivity and help control blood sugar levels in individuals with type 2 diabetes, although research findings are inconsistent. Some studies have demonstrated significant improvements in blood glucose control when cassia cinnamon is used as an adjunct to usual care. Its anti-inflammatory and antioxidant properties may also help with inflammation and digestive issues. The effect sizes vary across studies, and benefits may be observed within a few weeks to months of consistent use. However, due to the variability in study results, the clinical significance of these benefits remains somewhat uncertain.
How it works
Cassia cinnamon is believed to enhance insulin sensitivity, potentially through its bioactive compounds like cinnamaldehyde. It may interact with the endocrine system to improve glucose metabolism. The primary biological pathways involve insulin receptors and related signaling pathways. However, the exact mechanisms and the bioavailability of cassia cinnamon's active compounds are not yet fully understood. Further research is needed to elucidate the precise molecular targets and interactions within the body.
Side effects
Cassia cinnamon is generally considered safe when consumed in moderate amounts (1-2 grams per day) for short to medium terms. Common side effects include skin irritation and allergic reactions when applied topically. Uncommon side effects may include gastrointestinal upset. Rare but serious side effects include liver damage due to the high coumarin content, especially in individuals with pre-existing liver conditions. Potential drug interactions with diabetes medications exist, and high doses should be avoided, particularly in those with liver disease. Pregnant women and individuals with liver disease should consult a healthcare provider before use. It is important to adhere to recommended dosage guidelines to minimize the risk of adverse effects.
Dosage
The minimum effective dose of cassia cinnamon is around 1 gram per day, with optimal dosage ranges between 1-2 grams per day. Doses exceeding 6 grams per day should be avoided due to the high coumarin content and potential for liver damage. Consistent daily intake is recommended for potential benefits. The powdered form is commonly used. Bioavailability may vary based on preparation and individual factors. It is advisable to consult with a healthcare provider to determine the appropriate dosage and ensure safe usage, especially for individuals with underlying health conditions or those taking medications.
FAQs
How should cassia twig extract be used?
Cassia twig extract should be used under the guidance of a healthcare provider, especially for diabetes management. Consistent daily use is recommended, and it is not a replacement for conventional diabetes treatment but may be used as an adjunct.
What are the safety concerns with cassia twig extract?
High doses of cassia twig extract can lead to liver issues due to its coumarin content. It's important to adhere to recommended dosage guidelines and consult with a healthcare provider, especially if you have pre-existing liver conditions.
What results can I expect from using cassia twig extract?
Results are variable, with some individuals experiencing improved blood sugar control. It is essential to manage expectations and understand that it may not work for everyone. Individual responses can vary significantly.
Is cassia twig extract safe for everyone?
Pregnant women and individuals with liver disease should consult a healthcare provider before using cassia twig extract. It may not be safe for everyone, and professional medical advice is recommended.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/34408931/ – A systematic review and meta-analysis examined the impact of cassia bark on glucose and lipid control in type 2 diabetes. The study found insignificant reductions in key outcomes, suggesting limited benefits for glucose and lipid management in this population. The methodology involved a comprehensive search and analysis of relevant clinical trials.
- https://journals.lww.com/cmc/fulltext/2021/10000/clinical_research_on_cinnamomi_cortex__a_scoping.7.aspx – A scoping review highlighted conflicting results across studies using cassia cinnamon as an adjunct to usual care. Some studies showed significant improvements in HbA1c and blood glucose levels, while others did not. The review underscores the need for more consistent and rigorous research to determine the true efficacy of cassia cinnamon.
- https://www.webmd.com/vitamins/ai/ingredientmono-1002/cassia-cinnamon – Clinical studies have indicated that cassia cinnamon may improve insulin sensitivity, though the evidence is not consistent across all studies. This suggests that while some individuals may experience benefits, the effects can vary. The information is based on a compilation of various clinical studies and research findings.
- https://www.netmeds.com/health-library/post/cassia-plant-know-about-its-medicinal-uses-culinary-aromatic-and-cosmetic-properties – This article provides an overview of the medicinal uses, culinary applications, and aromatic properties of the cassia plant. It highlights the traditional uses of cassia in various cultures and its potential health benefits. The information is based on traditional knowledge and general scientific understanding.
Supplements Containing Cassia Twig Extract

Gui Zhi Alcohol Free
Hawaii Pharm

Gui Zhi
Hawaii Pharm

Liver Balance
Nature's Sunshine

Kidney Activator
Nature's Sunshine

VS-C
Nature's Sunshine

VS-C
Nature's Sunshine

Angelica Si Ni Teapills
Plum Flower

Joint Obstruction Teapills
Plum Flower

Wu Ling Teapills Wu Ling Wan
Plum Flower

Nature's Chi
Nature's Sunshine

Tiao He Cleanse
Nature's Sunshine

Channel Flow
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