Hops Cones Extract
Also known as: hops, hops cones extract, Humulus lupulus
Overview
Hops, scientifically known as *Humulus lupulus*, are the flowers of the hop plant primarily utilized in the brewing industry to impart bitterness and preserve beer. They contain a variety of beneficial compounds, including polyphenols, acyl phloroglucides, and beta acids (α-acids and β-acids), which are linked to various health benefits. Hops have historically been recognized for their ability to enhance sleep, regulate appetite, and demonstrate antioxidant effects. The extract can be found in several forms, including dried cones, powders, and liquid extracts, with supercritical CO₂ extraction being prominent for its improved bioavailability. While current research highlights hops extract's potential, further studies are needed to fully understand its long-term efficacy and safety profile.
Benefits
Research shows that hops extract can aid in appetite regulation by reducing acute energy intake, as seen in a double-blind study with healthy-weight men. Additionally, its antioxidant properties are validated through in vitro studies demonstrating inhibition of oxidative damage in blood platelets. Although traditional uses of hops for sleep aid suggest benefit, modern data remains largely anecdotal, and the effects on gut function are emerging topics. Most clinical studies primarily focus on healthy adults, indicating a gap in exploration concerning various demographic responses.
How it works
The mechanism of action of hops extract involves interaction with bitter taste receptors (T2Rs) in the gastrointestinal system, regulating gut function and appetite. Its antioxidant properties stem from its capability to mitigate oxidative and nitrative damage to lipids and proteins, primarily attributed to its polyphenolic and acyl phloroglucide components. Furthermore, these interactions may promote cardiovascular health by safeguarding against inflammatory responses.
Side effects
Hops extract is considered generally safe when dosed appropriately, although long-term safety remains inadequately explored. Documented side effects mainly include gastrointestinal discomfort, typically without significant differences compared to placebo. Rare side effects are not extensively recorded in research. No major drug interactions have been identified, but caution is advised when using hops extract alongside medications that influence gastrointestinal or sleep functions. Pregnant or breastfeeding women should exercise caution due to insufficient reproductive toxicity data.
Dosage
The suggested minimum effective dose for appetite regulation is approximately 125 mg of hops extract, while optimal dosages are not clearly established. Although no maximum safe dosage exists, high concentrations (up to 1.0 g/kg/day) have shown potential risks in animal studies. For appetite regulation benefits, consumption is advised before meals. The absorption of hops extract can vary based on its form, with supercritical CO₂ extraction being favored for enhanced bioavailability. Formulation type and timing can significantly affect the extract's effectiveness.
FAQs
Is hops extract safe?
Yes, hops extract is generally safe at recommended doses, but prolonged use and interactions with medications should be monitored.
When should I take hops extract?
For appetite regulation, it's best to consume hops extract before meals. Timing for antioxidant effects is less critical.
What results can I expect from using hops extract?
Users may experience reduced energy intake, potential improvement in sleep quality, and antioxidant benefits.
Can I use hops extract for sleep problems?
While traditionally used for sleep disorders, evidence is mostly anecdotal, and it's advisable to consult a healthcare provider.
Research Sources
- https://www.ncbi.nlm.nih.gov/pubmed/29986087 – This systematic review examined the effects of hops on appetite regulation and found consistent evidence supporting its role in reducing energy intake, particularly noted in a well-controlled human study.
- https://www.ncbi.nlm.nih.gov/pubmed/29248707 – This research assessed the antioxidant effects of hops extract in vitro, demonstrating significant inhibition of lipid and protein oxidative damage, suggesting potential cardiovascular protection.
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