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Cynatine HNS

Q: How quickly can results be expected?

Improvements in hair and nail parameters have been observed within 90 days of daily supplementation with Cynatine HNS.

Q: Is Cynatine HNS safe for long-term use?

No adverse effects have been reported in 90-day trials; however, long-term safety data are limited, and further research is needed.

Q: Does Cynatine HNS work for all hair types?

Clinical data are primarily limited to adult females; broader applicability to different hair types and populations requires further study.

Q: Can Cynatine HNS reverse hair loss?

It may improve hair growth phase duration and reduce hair loss but is not a treatment for underlying alopecia conditions.

Q: Is it better than other keratin supplements?

Cynatine HNS is a patented, highly bioavailable form, but direct comparative studies with other keratin supplements are lacking.

Also known as: Cynatine HNS, keratin peptides, hydrolyzed keratin

Overview

Cynatine HNS is a patented, bioavailable form of keratin peptides derived from sheep's wool. Keratin is a fibrous structural protein naturally found in hair, skin, and nails. As a dietary supplement, Cynatine HNS is primarily used to improve hair growth, strength, and luster, as well as nail strength and appearance. It is designed to replenish keratin levels in hair and nails, thereby supporting their structural integrity. Research includes randomized controlled trials (RCTs) demonstrating statistically significant improvements in hair growth parameters and nail strength. The quality of evidence is considered moderate, with well-conducted RCTs but a lack of independent systematic reviews and meta-analyses specifically on Cynatine HNS. It is composed primarily of amino acids such as cystine, serine, glutamic acid, and methionine.

Benefits

Cynatine HNS supplementation at 500 mg/day has demonstrated statistically significant improvements in hair growth parameters, including increased hair in the anagen (growth) phase and reduced hair loss after 90 days. Clinical trials have shown significant increases in key amino acid ratios critical for keratin structure, such as cystine, serine, glutamic acid, and methionine, indicating bioavailability and incorporation into hair proteins. Improvements in nail strength and appearance have also been reported. These benefits were observed in healthy adult females. While a broader review of keratin peptides suggests potential alleviation of osteoarthritis symptoms, this is not specific to Cynatine HNS and requires further validation. The increases in amino acid content and improvements in hair and nail parameters were statistically significant (p < 0.001), indicating robust effects within 90 days.

How it works

Cynatine HNS provides bioavailable keratin peptides and amino acids, especially cystine, a key component of keratin disulfide bonds that confer strength and resilience to hair and nails. These peptides are absorbed in the gastrointestinal tract and incorporated into keratinous tissues, supporting the synthesis and repair of hair and nail proteins. The primary biological pathway involves the provision of building blocks for keratin synthesis in hair follicles and nail matrix cells. Demonstrated bioavailability shows effective absorption and utilization of these peptides, leading to increased amino acid ratios in hair protein after supplementation.

Side effects

Cynatine HNS appears to be safe based on available clinical trial data, with no reported adverse effects in the primary RCT. Common, uncommon, and rare side effects have not been reported in studies to date. There are no documented drug interactions or specific contraindications identified. However, the available data is primarily limited to adult females, and the safety in pregnant or lactating women, as well as other populations, has not been established. Further research is needed to fully assess the safety profile in diverse populations and with long-term use.

Dosage

The minimum effective dose of Cynatine HNS is 500 mg per day, as used in clinical trials. The optimal dosage range is also 500 mg daily of Cynatine HNS keratin peptides, often combined with vitamins and minerals. The maximum safe dose has not been definitively established due to limited data, but 500 mg daily is the studied dose. Daily supplementation for at least 90 days is recommended to observe noticeable benefits. It is typically administered in oral capsules containing Cynatine HNS keratin peptides. The hydrolyzed form enhances bioavailability, and no specific cofactors are explicitly required, although vitamins and minerals included in tested formulations may support keratin synthesis.

FAQs

How quickly can results be expected?

Improvements in hair and nail parameters have been observed within 90 days of daily supplementation with Cynatine HNS.

Is Cynatine HNS safe for long-term use?

No adverse effects have been reported in 90-day trials; however, long-term safety data are limited, and further research is needed.

Does Cynatine HNS work for all hair types?

Clinical data are primarily limited to adult females; broader applicability to different hair types and populations requires further study.

Can Cynatine HNS reverse hair loss?

It may improve hair growth phase duration and reduce hair loss but is not a treatment for underlying alopecia conditions.

Is it better than other keratin supplements?

Cynatine HNS is a patented, highly bioavailable form, but direct comparative studies with other keratin supplements are lacking.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC4214097/ – This randomized, double-blind, placebo-controlled study investigated the effects of Cynatine HNS on hair and nails. The study found that participants taking Cynatine HNS experienced significant improvements in hair growth, strength, and appearance, as well as nail strength, compared to the placebo group.
https://pubmed.ncbi.nlm.nih.gov/25386609/ – This study evaluated the efficacy of Cynatine HNS in improving hair and nail health. Results indicated that Cynatine HNS supplementation led to statistically significant improvements in hair growth parameters and nail strength, suggesting its potential as a beneficial supplement for hair and nail health.
https://new.shapiromd.com/pages/studies – This page summarizes studies related to Cynatine HNS, highlighting its benefits for hair health. It emphasizes the ingredient's ability to improve hair growth, reduce hair loss, and enhance hair strength based on clinical trial results.
https://ift.onlinelibrary.wiley.com/doi/10.1111/1541-4337.13087 – This review discusses the potential of wool keratin, including Cynatine, as a novel protein source and its potential to alleviate symptoms of osteoarthritis. It supports the bioactivity and safety profile of Cynatine, though the primary focus is not on hair and nail benefits.
https://hairlove.com/blogs/hairlove/ingredient-highlight-cynatine-hns – This blog post highlights Cynatine HNS as a key ingredient for hair health, emphasizing its bioavailability and effectiveness in improving hair strength and growth. It provides a general overview of the ingredient's benefits based on available research.