Lactium 90
Also known as: Lactium, Milk Protein Hydrolysate, Milk Peptide
Overview
Lactium is a bioactive peptide derived from the hydrolysis of milk proteins, specifically milk casein. It is a concentrated form of milk protein used primarily in dietary supplements to enhance sleep quality and reduce stress. Lactium works by influencing neurotransmitter activities related to sleep regulation and stress response, showing particular promise when combined with L-theanine. Although research is emerging, several small to moderate clinical trials suggest Lactium may improve sleep metrics and positively influence gut microbiota, particularly in adults suffering from sleep discomfort. Its popularity stems from its natural sources (milk), ease of incorporation into dietary regimens, and the increasing interest in bioactive compounds for health benefits. Formulations typically include Lactium in tablet form, often combined with other compounds like L-theanine to enhance efficacy.
Benefits
Research indicates several notable benefits associated with Lactium supplementation. Most prominently, Lactium has been shown to improve sleep quality significantly, as evidenced by a double-blind, randomized controlled trial involving 40 participants that reported enhancements in total sleep time (TST), decreased sleep onset latency (SOL), improved sleep efficiency (SE), and reduced wake after sleep onset (WASO) counts. Additionally, beneficial changes were observed in gut microbiota composition, with Lactium potentially supporting an increase in beneficial bacterial populations linked to sleep improvement. The primary population benefiting from Lactium use appears to be adults experiencing sleep issues, with improvements becoming noticeable within four weeks and continuing through eight weeks of consistent usage.
How it works
Lactium is believed to exert its effects primarily through the modulation of neurotransmitter activity in the brain. It likely influences the GABAergic system, which plays a significant role in sleep regulation by promoting relaxation and reducing anxiety. Furthermore, it may enhance the release of neurotransmitters such as serotonin and dopamine, which contribute to mood stabilization and sleep onset. Its interaction with the gut-brain axis may also imply additional benefits related to gut health and overall well-being.
Side effects
The safety profile of Lactium appears to be favorable based on available studies, which report no significant common side effects (greater than 5%). Uncommon side effects are not well-documented due to limited sample sizes, and no rare side effects (less than 1%) were reported. Although there are no specific contraindications for Lactium, individuals with milk protein allergies are advised to avoid it. Caution is warranted when combining Lactium with other CNS-altering substances, including sleep medications. Pregnant or breastfeeding women, as well as those with chronic health conditions, should consult healthcare professionals prior to initiating Lactium supplementation to ensure safety.
Dosage
The typical dosing for Lactium involves one packet containing a tablet of Lactium and a tablet of L-theanine, taken one hour before bedtime. While exact optimal dosage ranges have not been firmly established beyond this combination, this regimen has shown effective results in clinical studies. No maximum safe dosing limit has been identified in current literature, and users are encouraged to adhere to provided guidelines. Timing is crucial for efficacy, suggesting adherence to pre-bedtime supplementation to maximize potential benefits derived from Lactium. The supplement is commonly available in tablet form, and it is recommended that it be taken with water.
FAQs
When is the best time to take Lactium?
Take Lactium one hour before bedtime to optimize its sleep-enhancing effects.
Can Lactium be taken with other supplements?
Limited data exists on combining Lactium with other supplements; therefore, caution is advised.
What improvements should I expect from Lactium?
Users can expect improved sleep quality, including reduced sleep onset latency and increased sleep efficiency.
Is Lactium a sedative?
No, Lactium is not a sedative. Consistent use over several weeks is recommended for effects.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1419978/full – This study is a double-blind, randomized controlled trial examining the effects of Lactium and L-theanine on sleep disturbances in adults. It highlights significant improvements in sleep metrics and the gut microbiota, providing a strong evidence base for Lactium's efficacy.
- https://pubmed.ncbi.nlm.nih.gov/38864162/ – This article discusses the biochemical properties and health impacts of Lactium, emphasizing its safety and potential benefits for sleep quality enhancement, although emphasizing the need for larger studies.
- https://pubmed.ncbi.nlm.nih.gov/38953043/ – A further investigation into Lactium's effects on sleep disturbances, this study corroborates findings of improved sleep metrics in adults when supplemented, supporting its use in clinical practice.
- https://www.researchgate.net/publication/381914541_Dietary_supplementation_with_Lactium_and_L-theanine_alleviates_sleep_disturbance_in_adults_a_double-blind_randomized_placebo-controlled_clinical_study – This source provides detailed findings from an RCT exploring the combined supplementation of Lactium and L-theanine in improving sleep disturbances, reinforcing the safety profile and notable sleep improvements.
- https://sleep.org.au/common/Uploaded%20files/Public%20Files/Latest%20News/Research%20Review/Integrative%20Medicine%20Research%20Review%20Issue%201.pdf – This review addresses various dietary supplements for sleep improvement, featuring Lactium as a promising compound with emerging evidence supporting its efficacy.
