ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Proprietary Blend

Also known as: Sphaeranthus indicus, East Indian globe thistle, Mangifera indica, mango

Overview

Sphaeranthus indicus and Mangifera indica are herbal supplements derived from the flower heads and stem bark of these plants, respectively. Used primarily for enhancing physical performance, this proprietary blend aims to improve muscle strength, endurance, and overall body composition. The herbal extracts are typically standardized to maintain a consistent level of bioactive compounds, ensuring their efficacy in supplementation. Research maturity in this area is moderate, with some clinical trials demonstrating potential benefits, although more systematic reviews are warranted to deepen the understanding of long-term effects and interactions.

Benefits

The combination of Sphaeranthus indicus and Mangifera indica has shown notable benefits including significant improvements in muscle strength, endurance, and body composition among young male volunteers. Statistically significant enhancements were documented in strength measures (p-values < 0.0001) during a 56-day supplementation period. Additional benefits may include improved hormone levels such as testosterone, although these effects need further exploration beyond the initial population studied. The benefits seem more pronounced in younger populations, with further research required to assess efficacy across various demographics.

How it works

The exact mechanisms of action for this proprietary blend are not completely understood. However, it is believed to modulate muscle protein synthesis and hormonal regulation, affecting both the musculoskeletal and endocrine systems. Current literature does not define specific molecular targets for the blend but suggests influences on muscle metabolism and development. Absorption and bioavailability data for this specific combination remain limited, calling for more detailed studies.

Side effects

Sphaeranthus indicus and Mangifera indica are generally well-tolerated based on available studies, with no significant adverse events reported. Most literature does not document common, uncommon, or rare side effects. While the safety profile appears favorable, potential drug interactions have not been thoroughly studied, and the lack of specific contraindications or warnings means that caution should be practiced, particularly among pregnant individuals, children, and those with chronic health issues. Ongoing vigilance and further research are essential to fully elucidate any unseen risks.

Dosage

The minimum effective dosage for the proprietary blend has been established at 650 mg per day. However, optimal dosage ranges are still yet to be firmly established, and there is currently no defined maximum safe dose. Typically, the supplement is taken daily, commonly in capsule or tablet form. There is limited understanding regarding absorption factors specific to the blend, and no specific cofactors are noted as being required for efficacy.

FAQs

What are the practical usage concerns for this supplement?

Users should consult with healthcare professionals before starting any supplement regimen, especially considering personal health conditions.

How safe is this proprietary blend?

Based on the available studies, it is generally considered safe, but further research is necessary to confirm long-term safety.

What is the recommended timing for taking this supplement?

Daily dosing is standard for optimal benefits, although specific timing during the day is not defined.

What results can I expect from using this supplement?

Users may expect improved muscle strength and endurance, particularly with a routine of physical exercise.

Are there misconceptions about using supplements like this?

A common misconception is that significant muscle gains can be achieved solely through supplementation without exercise.

Research Sources

  • https://foodandnutritionresearch.net/index.php/fnr/article/view/8972 – This study is a randomized, double-blinded, placebo-controlled trial examining the effects of the proprietary blend on 40 young male volunteers over 56 days, showing significant improvements in muscle strength and endurance, although demographic scope was limited.
  • https://www.mcgill.ca/tb/files/tb/tb_stigma_measurement_guidance.pdf – This document provides guidance on measurement methodologies, although not specific to Sphaeranthus indicus and Mangifera indica, it demonstrates the necessity of proper measurement in research.
  • http://sif2022-production.s3.amazonaws.com/uploads/attachment/file_it/1788/Borrelli_2018_Drugs.pdf – Discusses various herbal supplements, providing context for the significance of studies like those involving Sphaeranthus indicus and Mangifera indica.
  • https://www.irdes.fr/documentation/syntheses/les-assistants-medicaux-en-france-et-dans-les-pays-de-l-ocde.pdf – A synthesis on healthcare assistants, illustrating the importance of healthcare guidance in managing supplement regimens.
  • https://www.adhdevidence.org/blog/supplements-helping-adhd-symptoms-anecdotal-or-proven – While focused on ADHD, this source underlines the necessity for evidence-based understanding of supplements, emphasizing the broader application of effective supplementation research.

Supplements Containing Proprietary Blend

Inspired By Nature Herbal Laxative by Vitamin World
38

Inspired By Nature Herbal Laxative

Vitamin World

Score: 38/100
K-Otic by All American EFX
58

K-Otic

All American EFX

Score: 58/100
Test Charge by All American EFX
33

Test Charge

All American EFX

Score: 33/100
Rely Detox Orange by Total Eclipse
55

Rely Detox Orange

Total Eclipse

Score: 55/100
Spiru-Pro Soy Protein Drink With Spirulina Natural Vanilla by Vitamin World
78

Spiru-Pro Soy Protein Drink With Spirulina Natural Vanilla

Vitamin World

Score: 78/100
Valerian Easy Sleep by Planetary Herbals
75

Valerian Easy Sleep

Planetary Herbals

Score: 75/100

Recommended Articles

Top Fertility Supplements for Women in 2025

Top Fertility Supplements for Women in 2025

By 2025, new FDA-approved fertility supplements, emphasizing organic ingredients, have shown significant effectiveness in aiding conception for women in their 30s.

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-scanner supplement apps vary in accuracy, especially with proprietary blends, but advancements are improving their reliability.

Legal Pre-Workout Supplements for Athletes

Legal Pre-Workout Supplements for Athletes

Legal pre-workout supplements like those with caffeine, beta-alanine, and creatine can safely enhance athletic performance without failing doping tests.

Top Testosterone Boosters for Cyclists: A Buyer's Guide

Top Testosterone Boosters for Cyclists: A Buyer's Guide

For cyclists, choosing testosterone boosters involves finding scientifically-backed, third-party tested products, with top picks including brands like TestoGen and Prime Male.