Get Your Personalized Supplement StackSupplement Stack Quiz

Maqui Berry Extract

Also known as: Aristotelia chilensis, Maqui Berry, Chilean Wineberry

Overview

Maqui berry (*Aristotelia chilensis*) is a fruit native to South America, particularly Chile, and has been traditionally used by the Mapuche people for its medicinal properties. It is exceptionally rich in anthocyanins, a type of polyphenol known for its potent antioxidant and anti-inflammatory effects. As a dietary supplement, Maqui berry extract is available in various forms, including freeze-dried powders and capsules. Research suggests that Maqui berry may help reduce oxidative stress, improve tear fluid production in individuals with dry eyes, and offer potential metabolic benefits such as improved glucose metabolism. While preliminary studies are promising, more extensive clinical trials are needed to fully validate its efficacy and safety across diverse populations and conditions. The extract is noted for its fast uptake and metabolism, making it a potentially effective natural health product.

Benefits

Maqui berry extract has demonstrated several potential health benefits, primarily attributed to its high anthocyanin content. It is effective in reducing oxidative stress and inflammation, which may alleviate symptoms of dry eye syndrome, as evidenced by increased tear fluid production in clinical pilot trials. Studies also suggest that Maqui berry may improve glucose metabolism and exhibit antiplatelet activity, potentially benefiting individuals with metabolic disorders or cardiovascular concerns. Smokers may experience reduced oxidative stress markers with Maqui berry supplementation. While these findings are promising, further research is needed to quantify the effect sizes and establish clinical significance across various conditions and populations. The strength of evidence varies, with pilot trials showing potential but requiring confirmation in larger, more rigorous studies.

How it works

Maqui berry's primary mechanism of action is attributed to its high concentration of anthocyanins, which act as potent antioxidants and anti-inflammatory agents. These bioactive compounds neutralize free radicals, reducing oxidative stress and subsequent inflammation throughout the body. The anthocyanins in Maqui berry, such as delphinidin and cyanidin derivatives, modulate stress pathways and influence metabolic homeostasis. The extract interacts with the cardiovascular, nervous, and immune systems by mitigating oxidative damage and inflammatory responses. Studies indicate that Maqui berry extract is rapidly absorbed and metabolized, with peak plasma concentrations of key anthocyanins observed within a few hours after ingestion.

Side effects

Maqui berry extract is generally considered safe, but comprehensive safety data, particularly regarding long-term use, is limited. Common side effects are not well-documented, but potential gastrointestinal upset, such as mild stomach discomfort, may occur in some individuals. Uncommon and rare side effects are currently unknown due to the limited data available. Maqui berry's antiplatelet activity suggests a potential interaction with anticoagulant medications, necessitating caution for individuals on blood thinners. While no specific contraindications have been established, caution is advised during pregnancy and lactation due to the lack of safety data in these populations. Individuals with bleeding disorders should also exercise caution. Further research is needed to fully characterize the safety profile of Maqui berry extract.

Dosage

The optimal dosage of Maqui berry extract varies depending on the specific application and the form of the supplement. Studies have used dosages ranging from 30 mg to 2 g per day. However, a minimum effective dose and a maximum safe dose have not been definitively established, necessitating further research. Freeze-dried powders and extracts are common forms of Maqui berry supplements. There are no specific timing recommendations for Maqui berry consumption; however, taking it with meals may help reduce potential gastrointestinal upset. Bioavailability can be influenced by the presence of other nutrients and the specific formulation of the extract. No specific cofactors are required for Maqui berry's efficacy.

FAQs

How should I take Maqui berry?

Maqui berry can be taken as a supplement in capsule or powder form, or incorporated into foods and beverages. Taking it with meals may help reduce potential gastrointestinal upset.

Is Maqui berry safe?

Maqui berry is generally considered safe, but more data is needed on long-term use and potential interactions. Consult with a healthcare provider before starting any new supplement.

What are the expected benefits of taking Maqui berry?

Users may experience improved antioxidant status and reduced inflammation. Benefits can vary, and it is not a cure-all. It is important to manage expectations and understand that results may vary.

Are there any drug interactions?

Maqui berry may interact with anticoagulants due to its antiplatelet activity. Consult with a healthcare provider if you are taking blood-thinning medications.

Can pregnant or breastfeeding women take Maqui berry?

Caution is advised during pregnancy and lactation due to a lack of safety data in these populations. Consult with a healthcare provider before use.

Research Sources

https://www.mdpi.com/2304-8158/13/6/838 – This study investigates the potential health benefits of Maqui berry extract, focusing on its antioxidant and anti-inflammatory properties. It highlights the role of anthocyanins in modulating oxidative stress and inflammation, suggesting potential applications in managing related health conditions. The research underscores the need for further clinical trials to validate these findings.
https://pubmed.ncbi.nlm.nih.gov/30423989/ – This bioavailability study examines how the body processes Maqui berry extract. It reveals that key anthocyanins are rapidly absorbed and metabolized, indicating a potentially efficient delivery of bioactive compounds. The study's findings support the use of Maqui berry as a source of readily available antioxidants.
https://pubs.rsc.org/en/content/articlelanding/2024/fo/d3fo02524a/unauth – This research explores the impact of Maqui berry polyphenols on oxidative stress and inflammation. It suggests that regular consumption of Maqui berry may help reduce markers of oxidative damage and inflammatory responses. The study contributes to the growing body of evidence supporting the health-promoting effects of Maqui berry.
https://pubmed.ncbi.nlm.nih.gov/25208615/ – This pilot trial investigates the effects of Maqui berry extract on individuals with dry eyes. The results indicate a significant increase in tear fluid production and a reduction in dry eye symptoms. While promising, the study emphasizes the need for larger, more comprehensive trials to confirm these findings.
https://www.mdpi.com/2072-6643/13/12/4273 – This systematic review provides a broad overview of the benefits of polyphenol intake, including from Maqui berries. It suggests that polyphenols may reduce oxidative stress and inflammation, contributing to overall health. The review highlights the need for more human intervention trials specifically focused on Maqui berries to strengthen the evidence base.