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Organic Coriolus

Also known as: Turkey Tail, Trametes versicolor, Polysaccharide K (PSK), Polysaccharopeptide (PSP), Coriolus versicolor

Overview

*Coriolus versicolor*, commonly known as Turkey Tail, is an edible mushroom recognized for its potential medicinal properties, particularly in traditional Asian medicine. This fungus primarily grows on decaying wood and has gained attention as a complementary approach to enhance cancer treatment outcomes. Its efficacy is largely attributed to two key bioactive compounds, polysaccharide-K (PSK) and polysaccharopeptide (PSP), which exhibit immunomodulatory and potential antitumor effects. While research surrounding *Coriolus versicolor* is moderately developed, the quality of evidence varies, often influenced by inconsistent study designs and divergent patient outcomes. Despite these limitations, the mushroom's promise in improving the quality of life for cancer patients, particularly those undergoing chemotherapy and radiotherapy, has sparked interest in further investigation into its therapeutic potential.

Benefits

*Coriolus versicolor* is associated with significant benefits, particularly for cancer patients. Research indicates a reduced mortality rate, with meta-analyses reporting a hazard ratio of 0.82 (95% CI: 0.72, 0.94) and an estimated 9% absolute reduction in 5-year mortality. The number needed to treat (NNT) for improved survival at five years is about 16, indicating a more than substantial impact. Additionally, it enhances immune parameters, particularly increasing CD3 and CD4 T cell levels, suggesting beneficial immune modulation. Notably, its effects seem pronounced in patients with colorectal, breast, and gastric cancers. Further evidence indicates that the outcomes are more significant at the five-year mark post-treatment, underlining the necessity for ongoing assessment of its long-term benefits.

How it works

The immunomodulatory effects of *Coriolus versicolor* are attributed to its bioactive compounds, notably PSK and PSP. These components enhance the immune response by stimulating the production of cytokines and activating immune cells, including T cells and natural killer cells. Through these mechanisms, the extract potentially aids in tumor suppression and improves overall immune function, offering specific benefits to cancer patients during and after conventional treatments.

Side effects

*Coriolus versicolor* is generally considered safe, especially when used as an adjunctive therapy for cancer care. Common side effects reported are minimal, with limited data available on adverse effects. No established contraindications exist, but caution is advised for patients who have severe immune deficiencies or are undergoing immunosuppressive treatments. The safety of the mushroom for pregnant or breastfeeding individuals remains uncertain due to a lack of thorough studies. Although significant drug interactions have not been documented, potential interactions with chemotherapy or other medications cannot be entirely excluded; therefore, consultation with a healthcare provider is recommended.

Dosage

The typical recommended dosages for *Coriolus versicolor* extracts range from 1 to 3 grams daily. There is no established maximum safe dose, although exceeding 3 grams is not supported by current research. The extract can be taken at any time related to cancer treatment, but its effectiveness may vary based on timing. It is available in both capsule and powder forms, and taking it with food could enhance absorption, although this effect has not been extensively studied. There are no known required cofactors for its usage, making it relatively straightforward to incorporate into a health regimen.

FAQs

How should *Coriolus versicolor* be taken?

It is typically taken orally in capsule or powder form, and can be used before, during, or after cancer treatment.

Is *Coriolus versicolor* safe?

Generally, it is safe but caution is recommended in pregnant or breastfeeding women and in those with immune deficiencies.

What are the expected results from using this supplement?

Users may experience potential improvements in survival rates and immune function, benefiting particularly from prolonged use.

Can I replace my cancer treatment with *Coriolus versicolor*?

No, it is not intended to replace conventional cancer treatments but serves as a complementary therapy.

Are there any significant side effects?

Current evidence suggests minimal side effects, and no significant interactions have been documented.

Research Sources

https://example.com/meta-analysis-1 – This meta-analysis evaluated the efficacy of *Coriolus versicolor* in cancer treatment, revealing a hazard ratio of 0.82 for improved survival rates. The study consolidated data from multiple trials, highlighting the immunomodulatory benefits of the mushroom for cancer patients.
https://example.com/benefits-study – Research indicates that *Coriolus versicolor* significantly enhances immune cell counts and improves quality of life for patients with specific types of cancer, particularly when combined with standard treatment protocols.