ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Organic Fermented Ashwagandha

Also known as: Ashwagandha, Indian Ginseng, Winter Cherry, Somnifera, Withania somnifera

Overview

Ashwagandha, scientifically recognized as *Withania somnifera*, is an adaptogenic herb primarily found in regions like India, Africa, and the Middle East. Extracted from the roots and leaves, it has been a pivotal component of Ayurvedic medicine for centuries. Notably rich in bioactive compounds such as withanolides, alkaloids, and flavonoids, Ashwagandha is renowned for its ability to enhance stress resilience, facilitate better sleep, mitigate anxiety, and promote overall well-being. Existing research emphasizes its therapeutic effects, especially in managing stress and improving sleep quality. However, the quality of evidence remains varied, often classified as moderate to low due to factors such as small sample sizes and methodological shortfalls.

Benefits

Ashwagandha supplementation presents multiple evidence-backed benefits. A systematic review found a significant enhancement in overall sleep quality (Standard Mean Difference: -0.59). Furthermore, it effectively reduces anxiety (SMD: -1.55) and stress levels (SMD: -1.75) in adult populations. Additionally, Ashwagandha has been associated with improved cardiovascular fitness, notably increasing VO2max in both healthy adults and athletes (mean difference: 3.00). The most pronounced effects are observed in individuals suffering from insomnia and among athletes. While statistically significant, the magnitude of improvements varies, showcasing effects ranging from small to moderate across disparate studies.

How it works

The therapeutic action of Ashwagandha can be attributed to its key bioactive compounds, particularly withanolides, which engage with crucial biological pathways such as the hypothalamic-pituitary-adrenal (HPA) axis, thereby modulating stress responses. Through these interactions, Ashwagandha exhibits anxiolytic properties by influencing GABA receptors and additional neurotransmitter systems. The herb also impacts the nervous, endocrine, and immune systems, reinforcing its adaptogenic characteristics and broad health advantages. Importantly, the bioavailability of Ashwagandha’s active compounds is notably improved in fermented forms.

Side effects

Generally, Ashwagandha is deemed safe for most individuals when consumed within recommended dosages; common side effects are infrequent. Some users may experience gastrointestinal issues or drowsiness, reported in less than 5% of cases. Serious adverse effects are rare and have not been significantly documented in clinical trials. Caution is recommended for individuals taking sedatives, thyroid medication, or blood thinners due to potential drug interactions. Pregnant and breastfeeding women, alongside individuals with autoimmune diseases, should avoid its use. Additionally, those with thyroid disorders require careful monitoring as Ashwagandha may alter thyroid hormone levels.

Dosage

The typical minimum effective dose of Ashwagandha for sleep and anxiety usually falls between 300-600 mg per day. For broader health benefits, a dosage of 600-1200 mg daily is commonly recommended, with certain studies advocating up to 12,000 mg daily for stress alleviation. Higher dosages exceeding 1200 mg are less frequently examined, and an explicit maximum safe dose has not been established. Ashwagandha can be administered once or twice daily without requisite timing restrictions; however, evening intake might enhance its sleep-related benefits. It's worth noting that the absorption of Ashwagandha is improved when ingested with food, particularly fatty meals.

FAQs

Is Ashwagandha safe?

Yes, Ashwagandha is generally considered safe but should be used cautiously by pregnant women and individuals with autoimmune conditions.

When should I take Ashwagandha?

It can be taken any time of day; however, taking it in the evening may help improve sleep quality.

What results can I expect?

Users may observe improvements in sleep, reduced anxiety, and enhanced physical performance within 8-12 weeks of consistent use.

Is it a stimulant?

No, Ashwagandha is not a stimulant and does not generally cause side effects when used as directed.

Recommended Articles

Best Supplements for Cortisol Reduction: A Scientific Guide

Best Supplements for Cortisol Reduction: A Scientific Guide

Adaptogens like Ashwagandha and Rhodiola, along with Phosphatidylserine, are effective in reducing cortisol levels, supported by scientific studies.

How Mood Support Supplements Affect Neurotransmitters

How Mood Support Supplements Affect Neurotransmitters

Mood support supplements contain ingredients that can influence neurotransmitter levels, improving mood and cognitive function.

Effective Ingredients in Hormone Supplements

Certain ingredients in hormone balance supplements show promise for hormonal health, though effectiveness varies and more research is needed.

Ashwagandha Benefits & Dosage Guide

Ashwagandha Benefits & Dosage Guide

Ashwagandha contains withanolides that offer stress reduction, improved sleep, and cognitive benefits at safe, moderate doses.