ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Horsetail Powder

Also known as: Equisetum arvense, Horsetail, Field Horsetail

Overview

Horsetail powder is derived from the dried aerial parts of *Equisetum arvense*, a plant with a history in traditional medicine for addressing urinary tract conditions, promoting wound healing, and supporting bone health. It contains bioactive compounds such as alkaloids, flavonoids, phenols, tannins, and notably, silica. Primarily, horsetail is utilized as a diuretic, to support bone and connective tissue health, and for its antioxidant and anti-inflammatory properties. While pharmacological studies have confirmed its bioactivities, high-quality clinical trials are still limited. Systematic reviews specifically focusing on horsetail as a supplement are scarce, although its chemical and biological effects have been documented in experimental and some clinical contexts. It is available in forms such as powder, capsules, and teas.

Benefits

Horsetail powder offers several potential health benefits, primarily supported by traditional use and preclinical studies. As a diuretic, it has been traditionally used to promote urine flow and support bladder and kidney health, although robust clinical evidence is limited. The presence of flavonoids and phenolic compounds contributes to its antioxidant and anti-inflammatory effects, demonstrated in vitro and in animal studies. Due to its high silica content, horsetail is believed to support bone mineralization and connective tissue repair, but definitive human clinical evidence is lacking. Some studies also suggest potential antimicrobial, anti-diabetic, and anti-tumor properties, but these findings are preliminary and mostly preclinical. Caution is advised for pregnant or breastfeeding women due to a lack of safety data.

How it works

Horsetail's effects are attributed to its bioactive compounds. Silica may promote collagen synthesis and bone mineralization. Flavonoids and phenols provide antioxidant activity by scavenging free radicals. However, it also contains thiaminase, an enzyme that can degrade vitamin B1 (thiamine), potentially leading to deficiency with prolonged use. It primarily acts on the renal system (diuretic effect), connective tissues (bone and skin), and possibly immune modulation via anti-inflammatory pathways. The molecular targets are not fully elucidated, but antioxidant enzymes and inflammatory mediators are likely involved. The absorption and bioavailability of silica and polyphenols in horsetail vary, and data are limited.

Side effects

Horsetail powder is generally considered safe for short-term use at typical doses, but long-term safety is not well established. Common side effects are not well-documented in clinical trials. Uncommon side effects include the potential for thiamine deficiency due to its thiaminase content, especially with prolonged use. Rare side effects include hypokalemia (low potassium levels) and hypoglycemia risk in diabetic patients due to its blood sugar-lowering potential. It may interact with diabetes medications (risk of hypoglycemia), diuretics, and drugs affected by potassium levels. It is contraindicated for pregnant or breastfeeding women and requires caution in patients with thiamine deficiency or those on medications affecting potassium. Special populations such as pregnant, breastfeeding, and diabetic patients, as well as those with vitamin B1 deficiency, should avoid or use it under medical supervision.

Dosage

Due to the lack of high-quality clinical trials, a minimum effective dose is not well defined. Traditional use suggests ranges from 300 mg to 900 mg of horsetail extract daily, but clinical validation is lacking. A maximum safe dose is not established; prolonged high doses may increase the risk of thiamine deficiency. It is typically taken in divided doses throughout the day. Powder, capsules, or teas are common forms; the powder form requires adequate hydration. Bioavailability may be influenced by the preparation method, and silica absorption is variable. Vitamin B1 supplementation may be advisable during prolonged use to prevent deficiency.

FAQs

Is horsetail powder safe for long-term use?

Prolonged use may cause thiamine deficiency due to the thiaminase enzyme; caution is advised. Consider supplementing with thiamine if using horsetail powder long-term.

Can horsetail powder help with bone health?

It contains silica, which may support bone mineralization, but clinical evidence is insufficient. More research is needed to confirm this benefit.

Does horsetail powder interact with medications?

Yes, especially diabetes medications and diuretics; consult healthcare providers before use to avoid potential complications.

How soon can benefits be expected?

There is no standardized timeline; traditional use suggests weeks to months. Individual results may vary significantly.

Is horsetail powder effective for weight loss or detox?

No strong clinical evidence supports these claims. It should not be relied upon for weight loss or detoxification purposes.

Research Sources

  • https://www.ncbi.nlm.nih.gov/books/NBK583202/ – This LiverTox review summarizes horsetail’s traditional uses and safety profile, highlighting its use for bladder and kidney conditions. It emphasizes potential risks such as thiamine deficiency and notes the limited clinical trial data available, while confirming its traditional medicinal applications.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC7321494/ – This PMC article focuses on the chemical composition and pharmacological properties of horsetail. It confirms antioxidant, anti-inflammatory, and antimicrobial bioactivities in vitro and in animal models, providing a biochemical basis for its traditional uses, though human clinical trial data are lacking.
  • https://www.webmd.com/vitamins/ai/ingredientmono-843/horsetail – This WebMD summary provides an overview of horsetail’s uses and side effects, emphasizing risks such as thiamine deficiency, hypokalemia, and interactions with diabetes medications. It highlights the absence of robust clinical trial evidence and recommends caution in vulnerable populations.
  • https://www.signos.com/blog/horsetail-herb – This article discusses the potential benefits of horsetail herb, including its high silica content and traditional uses for hair, skin, and nail health. It also mentions its diuretic properties and potential anti-inflammatory effects, while noting the need for more research to confirm these benefits.
  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.950012/full – This Frontiers in Pharmacology article explores the therapeutic potential of Equisetum species, including their antioxidant, anti-inflammatory, and wound-healing properties. It reviews the phytochemical composition and pharmacological activities, highlighting the need for further clinical studies to validate these effects in humans.

Supplements Containing Horsetail Powder

Hair/Skin/Nails by Vitamin World
63

Hair/Skin/Nails

Vitamin World

Score: 63/100
Hair Skin & Nails by Nature's Bounty Optimal Solutions
65

Hair Skin & Nails

Nature's Bounty Optimal Solutions

Score: 65/100
Hair Skin & Nails 3000 mcg by Kroger
68

Hair Skin & Nails 3000 mcg

Kroger

Score: 68/100
Hair Skin & Nails by Nature's Bounty Optimal Solutions
63

Hair Skin & Nails

Nature's Bounty Optimal Solutions

Score: 63/100
Hair Skin & Nails by Nature's Bounty
65

Hair Skin & Nails

Nature's Bounty

Score: 65/100
Hair Skin & Nails by H-E-B
65

Hair Skin & Nails

H-E-B

Score: 65/100
Hair Skin and Nails by Family Wellness
83

Hair Skin and Nails

Family Wellness

Score: 83/100
Hair - Skin - Nails by Vitamin World
82

Hair - Skin - Nails

Vitamin World

Score: 82/100