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organic Sesbania grandiflora

Also known as: Vegetable Hummingbird, Agati, August Tree, Sesbania grandiflora

Overview

Sesbania grandiflora is a small tree native to Asia and Australia, recognized for its rapid growth and traditional medicinal applications. Known for its bioactive compounds such as lignin, terpenes, and tripenes, this plant is utilized in various herbal formulations. It is reputed for its antioxidant, anti-diabetic, and hair health benefits, with notable evidence supporting its effects on hair density and thickness, along with its potential role in managing blood sugar levels. The plant is typically consumed as an extract and is gaining attention in research, although comprehensive systematic reviews and meta-analyses are still lacking. Overall, while its medicinal properties are increasingly documented, further extensive studies, particularly large-scale randomized controlled trials (RCTs), are required to confirm its efficacy.

Benefits

1. Hair Health: In a randomized controlled trial, *Sesbania grandiflora* extract (SesZen-Bio™) was found to improve hair density by 25% and hair thickness by 16.94% over 8 weeks—demonstrating clinical significance (p < 0.0001) [1][4]. 2. Anti-Diabetic Activity: It has been shown to inhibit α-amylase activity in vitro by up to 81% at a concentration of 1000 μg/ml, indicating strong potential as an anti-diabetic agent [2]. 3. Antioxidant Properties: Animal studies demonstrated that *Sesbania grandiflora* can reduce oxidative stress and protect against liver and kidney damage caused by smoking [5]. 4. Semen Quality: Preliminary evidence suggests improvement in semen quality in animals, though more human studies are necessary for validation [3]. The general population, particularly those experiencing hair loss or managing diabetes, may benefit most.

How it works

The primary mechanism of action of *Sesbania grandiflora* involves stimulating keratin production, which enhances hair follicle growth and overall hair health. Additionally, the extract exhibits significant inhibition of the α-amylase enzyme, leading to reduced postprandial hyperglycemia, a vital factor in diabetes management. It effectively interacts with both the skin and scalp to promote hair wellness and with the digestive system to ameliorate glucose absorption.

Side effects

Current research indicates *Sesbania grandiflora* extract is well tolerated, with no significant adverse effects reported in short-term studies. There have been no common side effects reported (>5% incidence), and data on uncommon or rare side effects is lacking. While drug interactions are not extensively documented, individuals taking diabetes medications or those with severe medical conditions should consult a healthcare provider prior to use. Pregnant women, children, and the elderly are advised to seek medical advice due to limited research on the safety of *Sesbania grandiflora* in these populations. Overall, while the current safety profile appears favorable, the lack of comprehensive data calls for caution in use.

Dosage

The minimum effective daily dose of *Sesbania grandiflora* extract for hair health benefits is approximately 250 mg, standardized to contain 0.5% biotin [1][4]. An optimal dosage range has yet to be established, but the effective range indicates that this studied dose is beneficial. The safety profile of higher doses remains uncertain due to a lack of evidence; however, the dosages used in the studies showed good tolerance. It is generally recommended to take the supplement with meals to enhance absorption. The extract is available in capsule form, suitable for oral administration.

FAQs

Is *Sesbania grandiflora* safe?

*Sesbania grandiflora* extract appears to be safe for short-term use; however, its long-term safety and potential interactions with medications require further investigation.

When is the best time to take this supplement?

It can be taken at any time during the day, though taking it with meals may improve absorption.

What results can I expect from supplementation?

Users may observe improvements in hair density and thickness as well as potential benefits in managing blood sugar levels.

Is this a cure for hair loss or diabetes?

No, *Sesbania grandiflora* is not a cure but may serve as a beneficial adjunct to other treatments.

Research Sources

https://www.ijclinicaltrials.com/index.php/ijct/article/download/782/424/4012 – This study is a randomized double-blind, placebo-controlled trial demonstrating significant improvements in hair health, with a 25% increase in hair density and 16.94% increase in hair thickness over an 8-week period.
https://japer.in/storage/models/article/LyOsj8K5giY6VB8dkZwvesvrSTdnkr6kgf9USEaamj4kyVQlUgPUKIduC604/anti-diabetic-activity-of-sesbania-grandiflora-alpha-amylase-inhibitory-effect.pdf – This in vitro study indicates that *Sesbania grandiflora* extract can significantly inhibit α-amylase activity, demonstrating potential as an anti-diabetic supplement.
https://researcherslinks.com/current-issues/Supplementing-Basal-Diet-with-Sesbania-Grandiflora-Tablet-SGtab-and-its-Effect-on-Semen-Quality-of-Kacang-Buck/33/1/6233/html – This study suggests potential improvements in semen quality with *Sesbania grandiflora* supplementation in animal models, but human studies are needed for further verification.
https://pubmed.ncbi.nlm.nih.gov/20814075/ – This research highlights the protective effects of *Sesbania grandiflora* against oxidative stress, based on animal studies demonstrating its ability to reduce damage in liver and kidney tissues.