ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

NONPROPRIETARY PROTEIN BLEND

Also known as: Protein blend, Mixed protein supplement, Protein Blend (Non-Proprietary)

Overview

A non-proprietary protein blend is a dietary supplement composed of multiple protein sources, typically combining animal-derived proteins like whey and casein with plant-based proteins such as pea, rice, or soy. These blends are designed to provide a comprehensive amino acid profile, supporting muscle growth, recovery, and overall nutritional needs. The combination of different protein sources allows for varying absorption rates, with fast-digesting proteins like whey providing immediate amino acids and slower-digesting proteins like casein offering sustained release. While extensive research supports the benefits of individual protein sources, studies specifically examining non-proprietary blends are less common. However, the general consensus is that protein supplementation, including blends, can enhance muscle strength and lean body mass when combined with resistance training. These blends are available in various forms, including powders, shakes, and bars, making them a versatile option for athletes and individuals seeking to increase their protein intake.

Benefits

Protein blends primarily enhance muscle strength and lean body mass when combined with resistance training. Meta-analyses have shown that protein supplementation, in general, increases lean body mass and strength, although the effect size can vary based on factors like age and training status. For example, studies have demonstrated moderate improvements in muscle strength and lean body mass with consistent protein supplementation. Secondary benefits may include support for endurance performance and overall athletic ability, although the evidence for these outcomes is less robust. These blends are particularly beneficial for athletes and individuals engaged in resistance training, aiding in muscle growth and repair. Benefits typically manifest over several weeks to months of consistent supplementation and training.

How it works

Protein blends stimulate muscle protein synthesis (MPS) by providing essential amino acids, particularly leucine, which is a key regulator of MPS. These amino acids interact with the muscular and skeletal systems to promote muscle growth and repair. Specifically, leucine interacts with mTOR (mechanistic target of rapamycin) signaling pathways to initiate MPS. The absorption and bioavailability of protein blends vary depending on the protein sources included; whey protein is generally absorbed quickly, while casein is absorbed more slowly, providing a sustained release of amino acids.

Side effects

Protein blends are generally considered safe when consumed in recommended amounts. Common side effects, affecting more than 5% of users, include gastrointestinal discomfort such as bloating or gas, particularly in sensitive individuals. Uncommon side effects, affecting 1-5% of users, may include allergic reactions to specific protein sources, such as lactose intolerance for dairy-based proteins. Rare side effects, affecting less than 1% of users, include severe allergic reactions. Potential drug interactions may occur with medications affecting kidney function or blood pressure. Individuals with severe kidney disease should consult a healthcare provider before increasing protein intake. Pregnant women, children, and individuals with specific dietary restrictions (e.g., vegans) should choose appropriate protein sources and consult with a healthcare professional.

Dosage

The minimum effective dose of a protein blend is typically around 20-30 grams of protein per serving. Optimal dosage ranges from 1.2 to 2.2 grams of protein per kilogram of body weight per day for athletes. It is generally recommended not to exceed 3 grams per kilogram of body weight per day. Common timing considerations include post-workout and before bedtime for supplementation. Liquid forms may be absorbed faster than solid forms. The presence of other nutrients, such as carbohydrates, can influence absorption rates. Adequate hydration is important when consuming protein supplements.

FAQs

How do I choose the right protein blend?

Select a blend that aligns with your dietary preferences (e.g., vegan, gluten-free) and consider the protein sources included to ensure a comprehensive amino acid profile.

Are protein blends safe?

Protein blends are generally safe, but monitor for gastrointestinal side effects such as bloating or gas. Individuals with kidney issues should consult a healthcare provider.

When is the best time to take a protein blend?

The best times to take a protein blend are post-workout and before bed to support muscle recovery and growth. Consistent use alongside training yields the best results.

What results can I expect from taking a protein blend?

With consistent use and training, you can expect improved muscle strength and lean body mass over time. However, excessive intake can be unnecessary and potentially harmful.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8978023/ – This study investigates the impact of protein supplementation on muscle strength and hypertrophy in resistance-trained individuals. The findings suggest that protein supplementation can significantly enhance muscle strength and lean body mass when combined with resistance training, highlighting the importance of adequate protein intake for optimizing training outcomes.
  • https://bjsm.bmj.com/content/52/6/376 – This meta-analysis examines the effects of protein supplementation on resistance exercise-induced gains in muscle mass and strength. The results indicate that protein supplementation can augment muscle hypertrophy and strength gains, with variations based on factors such as age, training status, and protein source. This underscores the role of protein in supporting muscle adaptation to resistance training.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC7926405/ – This review discusses the role of protein and amino acids in promoting muscle protein synthesis and recovery after exercise. It highlights the importance of essential amino acids, particularly leucine, in stimulating muscle protein synthesis and reducing muscle damage. The review emphasizes the need for adequate protein intake to support muscle adaptation and recovery in athletes and active individuals.
  • https://academic.oup.com/nutritionreviews/advance-article/doi/10.1093/nutrit/nuae200/7954494 – This article provides an overview of the current evidence on protein requirements for athletes and active individuals. It discusses the factors influencing protein needs, such as training intensity, duration, and individual characteristics. The article emphasizes the importance of optimizing protein intake to support muscle growth, repair, and overall athletic performance.
  • https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1455728/full – This study investigates the effects of different protein sources on muscle protein synthesis and recovery. The research compares the efficacy of animal-based and plant-based proteins in promoting muscle adaptation. The findings contribute to understanding the optimal protein sources for supporting muscle growth and recovery in various populations.