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Sacha Inchi

Also known as: Plukenetia volubilis L., Sacha Inchi, Inca Peanut, Plukenetia volubilis

Overview

Sacha Inchi (*Plukenetia volubilis*) is a plant native to the Amazon rainforest, prized for its seeds that are rich in polyunsaturated fatty acids (PUFAs), particularly α-linolenic acid (ALA, ω-3) and linoleic acid (ω-6). It is used as a dietary supplement due to its potential health benefits, including cardiovascular support and anti-inflammatory effects. The seeds are also a source of protein and antioxidants. Sacha Inchi oil, derived from the seeds, is the most common form of supplementation. Research on Sacha Inchi is emerging, with studies exploring its impact on lipid profiles, blood pressure, and gut health. While the quality of evidence is moderate, the existing randomized controlled trials suggest promising health benefits, warranting further investigation.

Benefits

Sacha Inchi oil supplementation has demonstrated potential cardiovascular benefits, including reductions in systolic and diastolic blood pressure, total cholesterol, and LDL-cholesterol, along with improvements in HDL-cholesterol levels. These effects have been observed in individuals with hyperglycemia, hypertension, and hyperlipidemia. Furthermore, Sacha Inchi may promote gut health by modulating gut microbiota and enhancing carbohydrate metabolism. Emerging research suggests potential anti-inflammatory and antioxidant properties, which may offer neuroprotective and dermatological benefits. However, more extensive research, including systematic reviews and meta-analyses, is needed to confirm these benefits across diverse populations and establish consistent effect sizes.

How it works

Sacha Inchi's primary mechanism of action is attributed to its high ALA content, which influences the ω-6/ω-3 fatty acid balance, potentially reducing inflammation and improving cardiovascular health. ALA is a precursor to other omega-3 fatty acids like EPA and DHA. Additionally, Sacha Inchi may modulate gut microbiota, enhancing carbohydrate metabolism and reducing immune system activity. While the exact molecular targets are not fully elucidated, it is believed that Sacha Inchi interacts with desaturases involved in fatty acid biosynthesis. ALA from Sacha Inchi oil is absorbed and can increase plasma levels of ALA and DHA.

Side effects

Sacha Inchi is generally considered safe with minimal side effects. The most commonly reported side effect is nausea, particularly during initial consumption. There are no consistently reported uncommon side effects. Rare side effects are not well-documented. Due to its high ALA content, Sacha Inchi may interact with anticoagulants, potentially increasing the risk of bleeding. Caution is advised for individuals with bleeding disorders or those taking blood-thinning medications. Pregnant or breastfeeding women should consult healthcare providers before using Sacha Inchi. While no specific contraindications have been established, it is essential to monitor for any adverse reactions and discontinue use if they occur.

Dosage

While a minimum effective dose is not well-established, typical dosages of Sacha Inchi oil range from 10-15 mL (1-2 tablespoons) per day for general health benefits. A maximum safe dose has not been established, and high doses may pose toxicity risks. It is recommended to start with a low dose to assess tolerance. Sacha Inchi oil can be taken with meals to enhance absorption. Cold-pressed oil is preferred due to its high bioactive content. Absorption may be enhanced with a balanced diet. There are no specifically identified required cofactors. Individuals should consult with a healthcare provider to determine the appropriate dosage based on their individual health status and needs.

FAQs

How should I start taking Sacha Inchi?

Begin with a low dose (e.g., 1 teaspoon of oil) to assess your tolerance, especially if you are new to ALA-rich supplements. Gradually increase the dose as tolerated.

Is Sacha Inchi safe to take with other medications?

It is generally safe, but monitor for nausea. Consult a healthcare provider if you are taking anticoagulants due to potential interactions with ALA.

When is the best time to take Sacha Inchi?

Take Sacha Inchi with meals for better absorption of its fatty acids. Consistency in timing can help in observing its effects on your health.

How long before I see results from taking Sacha Inchi?

Improvements in lipid profiles and blood pressure may be observed within weeks of consistent supplementation, but individual results may vary. It should be part of a balanced lifestyle.

Is Sacha Inchi a cure for health problems?

No, Sacha Inchi is not a cure-all. It should be part of a balanced diet and healthy lifestyle to support overall well-being, not as a sole treatment.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC11861005/ – This randomized, double-blind, placebo-controlled trial involving 54 patients with hyperglycemia, hypertension, and hyperlipidemia found that Sacha Inchi oil supplementation significantly reduced blood pressure and improved lipid profiles over a 12-week period. The study suggests potential cardiovascular benefits, but the small sample size and limited population diversity call for larger, more diverse studies to confirm these findings.
  • https://pubmed.ncbi.nlm.nih.gov/37979081/ – This study investigates the impact of Sacha Inchi on carbohydrate metabolism and gut microbiota. The research indicates that Sacha Inchi oil modulates gut microbiota and enhances carbohydrate metabolism, suggesting potential benefits for gut health. However, as an animal study using male Sprague Dawley rats, human studies are needed to validate these findings.
  • https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0319066 – This pharmacological review discusses the various properties of Sacha Inchi, including neuroprotection and anti-inflammatory effects. While the review provides insights into potential benefits, it is not a systematic review and lacks quantitative analysis, indicating a need for more rigorous studies to substantiate these claims.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC9483583/ – This study investigates the effects of Sacha Inchi on metabolic parameters. Results showed positive changes in lipid profiles and glucose metabolism, suggesting potential benefits for individuals with metabolic disorders. Further research is needed to confirm these findings and determine the optimal dosage and duration of supplementation.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8542186/ – This review discusses the potential health benefits of Sacha Inchi oil, focusing on its high content of omega-3 fatty acids. The review highlights the potential of Sacha Inchi oil to improve cardiovascular health and reduce inflammation. However, more research is needed to fully understand the mechanisms of action and potential side effects.

Supplements Containing Sacha Inchi

Performance Protein Vanilla by Vega Sport
78

Performance Protein Vanilla

Vega Sport

Score: 78/100
Perfomance Protein Chocolate by Vega Sport
65

Perfomance Protein Chocolate

Vega Sport

Score: 65/100
Skinny Gut Ultimate Shake Natural Vanilla Flavor by Renew Life
83

Skinny Gut Ultimate Shake Natural Vanilla Flavor

Renew Life

Score: 83/100
Performance Protein Chocolate by Vega Sport
85

Performance Protein Chocolate

Vega Sport

Score: 85/100
Performance Protein Vanilla by Vega Sport
80

Performance Protein Vanilla

Vega Sport

Score: 80/100
One All-In-One Nutritional Shake Vanilla Chai by Vega
68

One All-In-One Nutritional Shake Vanilla Chai

Vega

Score: 68/100
One All-In-One Nutritional Shake French Vanilla by Vega
73

One All-In-One Nutritional Shake French Vanilla

Vega

Score: 73/100
So Lean & So Clean Chocolate by Ora
88

So Lean & So Clean Chocolate

Ora

Score: 88/100
So Lean & So Clean Vanilla Chai by Ora
82

So Lean & So Clean Vanilla Chai

Ora

Score: 82/100