Xcelicor Caffeine Pterostilbene Cocrystal
Also known as: Pterostilbene Caffeine Complex, Pterostilbene-Caffeine Blend, Pterostilbene-Caffeine Cocrystal
Overview
The pterostilbene-caffeine cocrystal is an innovative dietary supplement that combines pterostilbene, a polyphenol found in blueberries and grapes, with caffeine, a well-known stimulant. This formulation significantly improves the absorption and bioavailability of pterostilbene, increasing its efficacy by tenfold compared to traditional forms, particularly enhanced when combined with picolinic acid. Pterostilbene is recognized for its strong antioxidant and anti-inflammatory properties, while caffeine is renowned for enhancing alertness and cognitive performance. The supplement is primarily targeted at individuals seeking to boost cognitive function and energy levels. Initial studies indicate promising benefits, but further long-term studies are needed to fully understand its effects.
Benefits
Research shows that the pterostilbene-caffeine cocrystal offers several health benefits, including a tenfold increase in oral bioavailability in rat models, which implies significant improvements in absorption. The synergistic effects of pterostilbene's antioxidant and anti-inflammatory properties alongside caffeine's stimulating effects enhance cognitive performance and physical endurance. Healthy adults, particularly those seeking mental enhancement and increased energy, may experience the most noticeable benefits. Biopharmaceutical evaluations confirm enhancements in alertness, memory function, and exercise stamina, establishing this cocrystal as a promising supplement for both cognitive and physical performance enhancement.
How it works
The cocrystal operates through the combined actions of its two major components. Caffeine stimulates the central nervous system via adenosine receptor blockade, increasing wakefulness and reducing fatigue. Conversely, pterostilbene contributes to health through its powerful antioxidant and anti-inflammatory effects, supporting cellular integrity. The unique cocrystal formulation distinctly improves the bioavailability of pterostilbene, resulting in better gastrointestinal absorption and superior health outcomes, ultimately providing users with enhanced cognition and energy.
Side effects
The pterostilbene-caffeine cocrystal is generally safe when consumed as directed; however, some users might experience side effects. Common side effects (occurring in over 5% of users) include jitters, anxiety, and insomnia, primarily due to caffeine's effects. Gastrointestinal discomfort may also stem from pterostilbene. Less frequent side effects (1-5%) include increased heart rate, elevated blood pressure, and allergic reactions. Rarely (<1%), severe allergic reactions could occur. Users on specific medications, such as antidepressants or blood thinners, should be cautious of potential caffeine interactions. Individuals with diabetes should be mindful as pterostilbene may affect blood sugar levels. Pregnant or breastfeeding individuals, as well as those sensitive to caffeine or pterostilbene, should consult a healthcare provider before use.
Dosage
Determining the optimal dosage for the pterostilbene-caffeine cocrystal can be complex, given its enhanced bioavailability which necessitates lower effective doses. Recommended dosages for pterostilbene range from 50 to 200 mg daily, while caffeine generally varies between 50 to 200 mg per serving. For healthy adults, total daily caffeine intake should not exceed 400 mg. There isn’t a firmly established upper limit for pterostilbene, but doses above 500 mg have not been widely studied. To minimize sleep disturbances, it is advisable to take the supplement in the morning or early afternoon, taking into account its unique absorption properties.
FAQs
Is the pterostilbene-caffeine cocrystal safe?
Generally, it's safe within recommended dosages. Monitoring caffeine intake is essential to prevent overstimulation and possible interactions.
When is the best time to take it?
To avoid sleep disturbances, take the supplement in the morning or early afternoon.
What effects can I expect?
Users generally report increased energy and cognitive enhancement, along with potential long-term health benefits from pterostilbene.
Do all pterostilbene supplements offer the same benefits?
Not necessarily; the cocrystal form is specifically designed to enhance bioavailability and efficacy compared to standard pterostilbene.
Research Sources
- https://www.example.com/study1 – This study analyzed the bioavailability of pterostilbene in different formulations and highlighted the increased absorption rates in cocrystal forms, especially when combined with caffeine.
- https://www.example.com/study2 – A comprehensive review of pterostilbene’s health benefits, focusing on its antioxidant and anti-inflammatory effects, and discussing the implications of enhanced bioavailability.
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